Media Gallery

Mitotic Spindle

January 22nd, 2009  |  Published in Media Gallery

Model of the mitotic spindle and an isosurface from a 3D stack of fluorescence images of a real mitotic spindle. The model has been manually placed relative to the image data. A "make it better" button in the FluoroSim module of the CISMM Microscope Simulator will optimize the fit of the geometric model to the image information by forward simulation of the fluorescence microscope imaging process.

Model of the mitotic spindle and an isosurface from a 3D stack of fluorescence images of a real mitotic spindle. The model has been manually placed relative to the image data.

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Fibrin Networks

January 22nd, 2009  |  Published in Media Gallery

Here is an example of a series of fibrin networks formed between ridges of optical glue.  Perhaps they formed from a sheet?

Here is an example of a series of fibrin networks formed between ridges of optical glue. Perhaps they formed from a sheet?

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Fibrin Sheets

January 22nd, 2009  |  Published in Media Gallery

Molecularly thin fibrin sheets have been observed during experiments in our group.  There is some evidence that these sheets develop into fibrin networks.  Here is one image showing perhaps this exact phenomenon.  A sheet is laying across ridges made of hardened optical glue.  However the sheet appears to be separating into individual fibers.

Molecularly thin fibrin sheets have been observed during experiments in our group. There is some evidence that these sheets develop into fibrin networks. Here is one image showing perhaps this exact phenomenon. A sheet is laying across ridges made of hardened optical glue. However the sheet appears to be separating into individual fibers.

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Adenovirus with DNA

January 22nd, 2009  |  Published in Media Gallery

This image of adenovirus on a silicon substrate was scanned using the nanoManipulator. An adenovirus capsid has disrupted, spilling its DNA onto the surface in a tangle. The portion of the image above a certain height has been made semitransparent by adding an opacity texture. This enables us to see through the image to the icosahedral model of an adenovirus drawn with the virus in the upper left corner. Surface color is according to height. The surface has a slight slope, resulting in uniform blue, gray, and red areas.

This image of adenovirus on a silicon substrate was scanned using the nanoManipulator. An adenovirus capsid has disrupted, spilling its DNA onto the surface in a tangle. The portion of the image above a certain height has been made semitransparent by adding an opacity texture. This enables us to see through the image to the icosahedral model of an adenovirus drawn aligned with the virus in the upper left corner. Surface color is according to height. The surface has a slight slope, resulting in uniform blue, gray, and red areas.

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A Tracked Strand of DNA

January 21st, 2009  |  Published in Media Gallery

A strand of DNA tracked using cores. The red curve is the core. The blue curves are the DNA edges implied by the core location and radius.

A strand of DNA tracked using cores. The red curve is the core. The blue curves are the DNA edges implied by the core location and radius.

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3DFM User Interface

January 21st, 2009  |  Published in Media Gallery

This shows the 3 Dimensional Force Microscope's User Interface design as of 9/25/2002. It shows the tracked bead in green, the surface carved out by the bead as it traveled, a yellow trace of the bead's path, and a video image of the sample including the bead. We are continually adding to the system to meet the needs of particular experiments.

This shows the 3 Dimensional Force Microscope

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Isosurface of Flourescence

January 21st, 2009  |  Published in Media Gallery

This image shows a 3D isosurface of fluoresence in a fixed human ephethelial lung cell culture. The lower surface is of the cells and cilia; the upper is the mucus layer above.

This image shows a 3D isosurface of fluoresence in a fixed human ephethelial lung cell culture. The lower surface is of the cells and cilia; the upper is the mucus layer above.

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Multivariate Visualization

January 21st, 2009  |  Published in Media Gallery

Three data sets are shown in this AFM image: topography is mapped directly to height, friction is mapped to color, and areas of high adhesion (normal to surface) are circled by contour lines.

Three data sets are shown in this AFM image: topography is mapped directly to height, friction is mapped to color, and areas of high adhesion (normal to surface) are circled by contour lines.

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TEM Simulator Movie

September 9th, 2003  |  Published in Media Gallery

Movie

This is a movie of a TEM simulation of curved single wall nanotube being moved over an amorphous carbon background. It runs at 12 fps.

temsimulator2

This is a longer version of the same movie.  Both movies were made using a graphics-hardware-accelerated simulator produced by David Borland as part of our accelerated microscope simulation and analysis work.  The curved nanotube shown in the video is moved by hand using a 6-degree-of-freedom manipulation device while the background thickness is adjusted.  The combined background + tube simulation is run at 12 frames/second.

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NanoRod Stands on End in 3DFM

July 25th, 2003  |  Published in Media Gallery

Movie

In this clip, we start with a NanoRod flat on the substrate, and are able to use the magnets to get the rod to stand up vertically on the coverslip. We then apply an orbitting voltage, and watch the rod’s tip move in a square-like orbit.

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