Events
Force Measurement and Manipulation in Biological Microscopy
Learn the theory and techniques of measuring forces in biological samples
Fifth Offering, September 22-25 2009
Presented by
Computer Integrated Systems for Microscopy and Manipulation
An NIH NIBIB Biotechnology Resource Center
at The University of North Carolina at Chapel Hill
CISMM Stimulus Package
!Registration FREE this year for NIH-funded researchers!

Simulated view of magnetic bead attached to a cilium being pulled by UNC’s unique 3D force microscope.
Course Content:
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Half of course will be spent with attendees using Atomic Force Microscopy and nanoManipulation and 3D magnetic force systems on live biological samples. These include tutorials on Fibrin Mechanics, Microfluidics, and Live Cell Mechanics.
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Theory and applications in force measurement of combined AFM-optical microscope, optical laser trap microscope, and UNC’s unique 3D Force Microscope.
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Overview of mechanisms of force generation in biology and consequences at molecular and cellular level.

Overlay of data from light microscope and AFM. Quantum Dot labels on fibrin fibers move apart (yellow arrows) showing stretching of the fiber when manipulated with the AFM tip (position shown with blue arrows).
Who Should Come?
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Individuals with an undergraduate education in science and some experience with biology.
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graduate students in biology or physics, or industry personnel wanting to understand the forefront of force measurements.
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Researchers interested in forces in cell cultures, cells, biophysical fibers, cytoskeletal components, and single molecules, such as DNA.
Instructors: Professors Richard Superfine, Michael Falvo, Russell M. Taylor II, and Timothy O’Brien
Fee: $775 (includes lab supplies) !Registration FREE this year for NIH-funded researchers!
Location: Chapel Hill, NC (served by Raleigh-Durham Airport)
Presented with support from : The University of North Carolina at Chapel Hill, NIH National Institute for Biomedical Imaging and Bioengineering, Center for Computer Integrated Systems for Microscopy and Manipulation, The UNC Roadmap Executive Committee for the Vice Chancellor for Research and Economic Development, and Asylum Research
To apply, contact Cassandra (919)-962-4057.
Registration is open now! Space is limited!
NOTE: Applications will be kept in order and we will notify you of acceptance based on space availability. There are 18 seats available for this year of the workshop.
Hotel information can be found here.
Please contact Cassandra Houston at houstonc@physics.unc.edu if you have any questions or if you need campus parking.





